Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gfra1  glial cell line derived neurotrophic factor family receptor alpha 1   (Synonyms: GDNFR-alpha, GFR alpha-1)
Results	Reference
1	J:346054 Baur K, Carrillo-Garcia C, San S, von Hahn M, Strelau J, Holzl-Wenig G, Mandl C, Ciccolini F, Growth/differentiation factor 15 controls ependymal and stem cell number in the V-SVZ. Stem Cell Reports. 2024 Mar 12;19(3):351-365
1	J:138626 Callahan T, Young HM, Anderson RB, Enomoto H, Anderson CR, Development of satellite glia in mouse sympathetic ganglia: GDNF and GFRalpha1 are not essential. Glia. 2008 Oct;56(13):1428-37
1*	J:254788 Chen Z, Donnelly CR, Dominguez B, Harada Y, Lin W, Halim AS, Bengoechea TG, Pierchala BA, Lee KF, p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling. Cell Rep. 2017 Oct 17;21(3):707-720
1*	J:308929 De Vincenti AP, Alsina FC, Ferrero Restelli F, Hedman H, Ledda F, Paratcha G, Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation. Development. 2021 Aug 15;148(16):dev197020
1	J:330530 Dura M, Teissandier A, Armand M, Barau J, Lapoujade C, Fouchet P, Bonneville L, Schulz M, Weber M, Baudrin LG, Lameiras S, Bourc'his D, DNMT3A-dependent DNA methylation is required for spermatogonial stem cells to commit to spermatogenesis. Nat Genet. 2022 Apr;54(4):469-480
1	J:54911 Fundin BT, Mikaels A, Westphal H, Ernfors P, A rapid and dynamic regulation of GDNF-family ligands and receptors correlate with the developmental dependency of cutaneous sensory innervation. Development. 1999 Jun;126(12):2597-610
1	J:217593 Garcia TX, Farmaha JK, Kow S, Hofmann MC, RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Development. 2014 Dec;141(23):4468-78
1*	J:82456 Gianino S, Grider JR, Cresswell J, Enomoto H, Heuckeroth RO, GDNF availability determines enteric neuron number by controlling precursor proliferation. Development. 2003 May;130(10):2187-98
1	J:196480 Grisanti L, Clavel C, Cai X, Rezza A, Tsai SY, Sennett R, Mumau M, Cai CL, Rendl M, Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol. 2013 Feb;133(2):344-53
1	J:202516 Grisanti L, Rezza A, Clavel C, Sennett R, Rendl M, Enpp2/Autotaxin in dermal papilla precursors is dispensable for hair follicle morphogenesis. J Invest Dermatol. 2013 Oct;133(10):2332-9
1	J:293102 Heinrich A, Potter SJ, Guo L, Ratner N, DeFalco T, Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis. Cell Rep. 2020 Apr 14;31(2):107513
1	J:332398 Khan MN, Cherukuri P, Negro F, Rajput A, Fabrowski P, Bansal V, Lancelin C, Lee TI, Bian Y, Mayer WP, Akay T, Muller D, Bonn S, Farina D, Marquardt T, ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control. PLoS Biol. 2022 Dec;20(12):e3001923
1*	J:279870 Makino Y, Jensen NH, Yokota N, Rossner MJ, Akiyama H, Shirahige K, Okada Y, Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression. Sci Rep. 2019 Apr 15;9(1):6063
1	J:193051 Marks C, Belluscio L, Ibanez CF, Critical role of GFRalpha1 in the development and function of the main olfactory system. J Neurosci. 2012 Nov 28;32(48):17306-20
1	J:199284 Munoz-Bravo JL, Hidalgo-Figueroa M, Pascual A, Lopez-Barneo J, Leal-Cerro A, Cano DA, GDNF is required for neural colonization of the pancreas. Development. 2013 Sep;140(17):3669-79
1*	J:328290 Nakagawa T, Jorg DJ, Watanabe H, Mizuno S, Han S, Ikeda T, Omatsu Y, Nishimura K, Fujita M, Takahashi S, Kondoh G, Simons BD, Yoshida S, Nagasawa T, A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis. Cell Rep. 2021 Oct 19;37(3):109875
1*	J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139
1*	J:258304 Pui HP, Saga Y, NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes. Mech Dev. 2018 Feb;149:27-40
1	J:327897 Rios AS, Paula De Vincenti A, Casadei M, Aquino JB, Brumovsky PR, Paratcha G, Ledda F, Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation. Development. 2022 Aug 15;149(16):dev200583
1	J:334500 Ruthig VA, Yokonishi T, Friedersdorf MB, Batchvarova S, Hardy J, Garness JA, Keene JD, Capel B, A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells. Biol Reprod. 2021 Apr 1;104(4):861-874
1	J:251552 Sergaki MC, Ibanez CF, GFRalpha1 Regulates Purkinje Cell Migration by Counteracting NCAM Function. Cell Rep. 2017 Jan 10;18(2):367-379
1	J:256225 Sergaki MC, Lopez-Ramos JC, Stagkourakis S, Gruart A, Broberger C, Delgado-Garcia JM, Ibanez CF, Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRalpha1 or RET Impairs Normal Cerebellar Motor Learning. Cell Rep. 2017 Jun 6;19(10):1977-1986
1*	J:251222 Sun F, Xu Q, Zhao D, Degui Chen C, Id4 Marks Spermatogonial Stem Cells in the Mouse Testis. Sci Rep. 2015 Dec 1;5:17594
1	J:191888 Suzuki H, Dann CT, Rajkovic A, Generation of a germ cell-specific mouse transgenic cherry reporter, Sohlh1-mCherryFlag. Genesis. 2013 Jan;51(1):50-8
1*	J:154912 Suzuki H, Sada A, Yoshida S, Saga Y, The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3. Dev Biol. 2009 Dec 15;336(2):222-31
1	J:205498 Tsai SY, Sennett R, Rezza A, Clavel C, Grisanti L, Zemla R, Najam S, Rendl M, Wnt/beta-catenin signaling in dermal condensates is required for hair follicle formation. Dev Biol. 2014 Jan 15;385(2):179-88
1	J:332220 Uchida A, Imaimatsu K, Suzuki H, Han X, Ushioda H, Uemura M, Imura-Kishi K, Hiramatsu R, Takase HM, Hirate Y, Ogura A, Kanai-Azuma M, Kudo A, Kanai Y, SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse. Nat Commun. 2022 Dec 21;13(1):7860
1	J:162904 Yamaji M, Tanaka T, Shigeta M, Chuma S, Saga Y, Saitou M, Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction. 2010 Feb;139(2):381-93
1	J:262197 Zechel S, Fernandez-Suarez D, Ibanez CF, Cell-autonomous role of GFRalpha1 in the development of olfactory bulb GABAergic interneurons. Biol Open. 2018 May 18;7(5):bio033753